Expert Bioprocess Designer Suite
Seven apps, one chemistry engine
Each app answers a question you actually have, about one part of the process. They share the same engine, so a buffer designed in one app gives the same pH and composition in another.
In beta now
In beta
PD · Formulation
Expert Buffer Designer
“What will this buffer's pH actually be at 4 °C instead of 25 °C — and how much has it moved?”
Design one buffer from first principles: what to weigh out, the pH you'll really get, and how it moves with temperature, salt and weighing error.
What it does →
PD · MSAT
Expert Solution Operations Designer
“After I titrate, dilute and condition a pool — what is actually in the tank now?”
Follow one vessel through make, add, titrate and dilute steps, with the pH and the composition after every one.
What it does →
USP · Cell culture
Expert Bioreactor Designer
“How will pH control behave once the cells start making acid — and will my base addition keep up?”
Simulate a CHO culture with its feeds and its DO and pH control, and see which limit binds first — and when.
What it does →The beta is by invitation, runs in the browser, and costs nothing to join. How to join →
Coming next
Coming soonThese four share the same engine and are in development. Each joins the beta once it has been through its own round of checks.
Formulation · DSP
Expert UF/DF Designer
“Why did my retentate pH drift away from the diafiltration buffer — and what buffer should I have used instead?”
Model ultrafiltration and diafiltration, including the Donnan effect that pulls a concentrated protein's pH and excipients away from the buffer.
MSAT · Facility
Expert Buffer Stock Blending Designer
“Can my skid actually make this buffer from the stocks I hold — and is blending it cheaper than preparing it?”
Design buffer stock-blending skids: which buffers a skid can make from the stocks you hold, and how prep strategies compare.
DSP · Purification
Expert Chromatography Designer
“For a protein with this pI, where should I start the gradient — and should this be CEX or AEX?”
Plan ion-exchange steps from the protein's charge, including the pH excursions a salt step causes on the column.
MSAT · Manufacturing
Expert Process Designer
“Across a twelve-batch campaign, do I run out of buffer or tank space — and on which day?”
Plan a whole campaign — upstream, downstream, buffers, tanks and the schedule — and find out whether you run short, and when.
Also here: the original app
Expert Buffer Designer Classic, the first app we released, still runs on the web and on iOS. The new Expert Buffer Designer in the suite is its successor. About the classic app →