Buffer Design for Biopharmaceutical Processes: An Online Tool for Designing and Understanding Buffers
The buffer-design method behind Expert Buffer Designer: buffer chemistry, a three-step design workflow, and robustness analysis.
Read the article ↗In the news
Our apps grow out of published work. The buffer-design method behind Expert Buffer Designer is described in BioProcess International, and the open-source NIIMBL–BioPhorum Buffer Stock Blending System behind Expert Buffer Stock Blending Designer is evaluated in the PDA Journal. Natraj Ram and Adharsh Ravi wrote the first; Natraj Ram is lead author of the second.
Published
The buffer-design method behind Expert Buffer Designer: buffer chemistry, a three-step design workflow, and robustness analysis.
Read the article ↗The peer-reviewed evaluation of the open-source NIIMBL–BioPhorum Buffer Stock Blending System, the work behind Expert Buffer Stock Blending Designer.
Read the paper ↗ DOI: 10.5731/pdajpst.2021.012660The Buffer Stock Blending System, open-sourced
The project page for the open-access buffer-manufacturing system; the prototype is housed at NIIMBL HQ.
Open ↗ BioPhorumThe industry collaboration behind the system — rethinking how buffers are prepared at manufacturing scale.
Open ↗ BioPhorumThe full open release: P&ID, bills of materials, I/O list, functional spec, FAT/SAT protocols, automation files.
Open ↗Coverage
Expert Buffer Stock Blending Designer takes that thinking and puts it in your hands — coming soon.